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Look it up! A bar displayed one row above the 10 uM row indicates that doses higher than 10uM were tested. National Institute of Rock Mechanics, Kolar Gold Fields, India is a Premier Research Institute engaged in Research, Training and Consultancy in all areas of Rock Engineering Spaces are allowed; punctuation is not allowed except for periods, hyphens, and underscores. Current Version Human MSigDB v2023.1.Hs updated March 2023. Broad Institute Scientists at the Broad Institute of MIT and Harvard are contributing to this global effort in a variety of ways. Our researchers use their expertise in creating, adapting, and applying a variety of technologies to enable science here and beyond. We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap). Here, several MEK inhibitors were found to have markedly increased anti-proliferative activity in BRAF mutant melanoma cells. Colored portion of top bar indicates the Broad assays in which this compound has been profiled. If you have a derivative work that is significantly different from what we provide and you would like to distribute it, please contact us with the details. The landscape of cancer cell line metabolismNat Med. Epub 2019 May 8. In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. Give each query a descriptive name that will help you identify your results. Please register to download the GSEA software and the MSigDB gene sets, All rights reserved. GPP Platform Staff - please click here to log in with Google. The tutorial describes the features of the heatmap. I hold a doctoral degree in Planning, Government, and Globalization from the School of Public and International Affairs, Virginia Polytechnic Institute and State University, Virginia, USA. Currently, the majority of samples sequenced are residual diagnostic samples from the Broad's large scale COVID-19 testing platform. This Spotlight is a part of our Mission Nikaalo Prelims-2023. Click on a heading to open a menu of articles. By leveraging the expertise and infrastructure available at both organisations, we aim to more rapidly deliver a high-quality DepMap. The COVID-19 testing center at the Broad is providing testing, training, and supplies to health agencies in eight hard-hit communities in the state. The goal of the Broad Cancer Cell Line Factory is to make it possible to convert any tumor sample into an organoid, cell line, or spheroid model. Broad Institute - Wikipedia and also the source for the gene set as listed on the gene set page. Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Gustafsdottir SM, Ljosa V, Sokolnicki KL, Wilson JA, Walpita D, Kemp MM, Seiler KP, Carrel HA, Golub TR, Schreiber SL, Clemons PA, Carpenter AE, Shamji AF. Financial with broad experience in all aspects of accounting, auditing and financial management. In short, BRAF mutation predicted sensitivity to MEK inhibition a finding later confirmed in phase III trials. Click the link in the email to reset your password. Broad Institute of MIT and Harvard.

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