This work presents more extensive results of separation of phenylsuccinic acid enantiomers by biphasic recognition chiral extraction (BRCE), which is an important intermediate of N-methyl--phensuximide and antitumor agents (in Fig. It was concluded that the aqueous solubility of the cocrystals is inversely related to their melting points and this trend can be linked to some packing features. Succinate thus serves as a direct electron donor to the electron transport chain, and itself is converted into fumarate. To purify, recrystallize the (S)-phenylsuccinic acid precipitate from wa- Abstract. Determine the mass of purified crystals and prepare a solution to analyze by polarimetry, first measure about 0.4g of your (S)-phenylsuccinic acid and then dissolve in exactly 10mL of HPLC-grade acetone. [5] In an aqueous solution, succinic acid readily ionizes to form its conjugate base, succinate (/sksnet/). Material Safety Data Sheet - Fisher Sci Add 2-propanol (approx. RECEIVE -15-CRUZ CREDITS. tiomer behind. (S)-(&)-Phenylsuccinic acid | CAS 4036-30-0 - SCBT Phenylsuccinic acid Molecular Formula CHO Average mass 194.184 Da Monoisotopic mass 194.057907 Da ChemSpider ID 86155 More details: Names Properties Searches Spectra Vendors Articles More Names and Synonyms Database ID (s) Validated by Experts, Validated by Users, Non-Validated, Removed by Users ()-Phenylsuccinic acid 10424-29- [RN] Google Scholar. The solid that results is now-resolved phenylsuccinic acid in its protonated form. The name derives from Latin succinum, meaning amber.In living organisms, succinic acid takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex 2 of the . Molecular Formula: C 10 H 10 O 4. Note that the two diastercomeric salts (S.S) and (R.S) differ in their mions (phenylsuccinate), which are nonsuper-posable mirror images, but have identical cations (L-proline). Enantioseparation of Phenylsuccinic Acid Enantiomers by Solvent Commun. RECEIVE -15-CRUZ CREDITS. In Commun. [24] This pathway is exploited in metabolic engineering to net generate succinate for human use. To begin, dissolve 1.94g of racemic phenylsuccinic acid into 50mL of isopropanol in a 100mL round bottom flask.
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